The Tigers fought valiantly, but the deep, experienced Harrisburg lineup was too much for the Marceline boys at home on Monday night.
With the 73-57 conference defeat, the Marceline falls to 1-1 in Lewis & Clark play on the season, and to 4-7 overall. Harrisburg moves to 9-3.
"They're a state-ranked team with a 12-man rotation," Marceline coach Paul Stevens said of a Harrisburg team that rosters more seniors than he has total players. "All of those kids can play.
"We're definitely getting better, I'm proud of the way our kids battled. The mistakes we're making are very fixable. Our kids are starting to listen and buying into what I want to do. We have to get better at moving our feet defensively, and it doesn't happen overnight."
In the first quarter, Marceline's eight-man lineup managed to remain within striking distance, trailing 18-16 entering the second. Harrisburg used a second-quarter burst to take a 38-28 lead at the halftime break.
At the end of the third quarter, Marceline trailed 56-44, but the Tigers went on an early fourth-quarter run to cut the Harrisburg lead to just five at 56-51.
From then on, however, the returning state-qualifier Bulldogs took complete control of the ballgame as Marceline's legs tired and foul trouble became an issue.
"After they cut it down to five, our guys did a good job of settling down and regaining their composure," Harrisburg coach Kyle Fisher said. "Marceline's got a handful of kids who can play, and they have a good gameplan for getting it inside or finding their shooters."
Levi Terrell led the charge for the Tigers with 25 points. Lance Gladbach and Desmond Harrison added respective tallies of 15 and 11 points.
Marceline plays again Friday when the Tigers travel to Schuyler County.